March 16, 2015 by Suzanne Elvidge in Big data, Big data in research, Drug development, Healthcare big data analysis

Digital hearts catalogued for big data study

As part of an effort to create new drugs for heart conditions, researchers are combining 3D videos of beating hearts with genetic information from 1600 volunteers in a big data project, according to a BBC News report. The research is being carried out at the Medical Research Council’s Clinical Sciences

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March 11, 2015 by Suzanne Elvidge in Big data, Big data in research, Drug development

Big data portal launched for Alzheimer’s drug discovery

Alzheimer’s disease is a frightening diagnosis, and its numbers are rising. While there are treatments available, these temporarily improve symptoms or slow development, but do not stop or reverse the disease. A public-private partnership led by the National Institutes of Health (NIH) could speed the rate of research and drug

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February 25, 2015 by Suzanne Elvidge in Big data in research, Data mining, Drug development

Combination data finds a possible path to personalised medicine

Personalised medicine is the Holy Grail of many drug development programmes, particularly in cancer medicine, where different drugs can be combined to improve efficacy and battle the development of resistance, which is the cause of 90% of the cases where metastatic cancer treatment fails. However, finding the right combination and

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February 01, 2015 by Suzanne Elvidge in Big data, Big data in research, Data analytics

Using big data to forecast the flu

Understanding more about flu trends could reduce disease spread, but big data efforts have overestimated cases. Researchers at UC San Diego are working to combine traditional data sources with big data to improve the quality of prediction. Even though the flu season is generally starting to abate around now, it

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January 30, 2015 by Suzanne Elvidge in Big data, Big data in research, Data analytics, Data mining

Major analysis of scans and DNA cracks brain’s genetic code

The brain is a very complex organ, and its structure is largely shaped by genetics. To understand more about how changes in the brain’s structure can lead to disease or alterations in behaviour, researchers analysed data from genome-wide association studies (GWAS) in the largest collaborative study of the brain to

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December 15, 2014 by Suzanne Elvidge in Big data, Big data in research, Data analytics, Data mining

Mining Twitter data opens a window on mental health

Social media generates a lot of information every day, from pictures of cats to discussions of science and politics. However, it can also been used to monitor outbreaks of disease, including infectious diseases such as flu and the winter vomiting virus. In some of the latest reports on the medical

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December 07, 2014 by Suzanne Elvidge in Big data, Big data in research, Data mining, Drug development

Data links gene to tamoxifen resistance

The hormone treatment tamoxifen is used to treat estrogen receptor-alpha (ER) positive breast cancers and to prevent their recurrence, but the lack of response in some tumors is an unmet medical need. Through data mining, researchers have made a link between the resistance and overexpression of a gene, MACROD2, which

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November 30, 2014 by Suzanne Elvidge in Big data, Big data in research, Data analytics, Data mining, Drug development

Using bioinformatics to create cancer vaccines

Biologists, immunologists and computational bioinformaticians have worked together to find protein mutations on cancer cells that could lead to new personalised vaccines. The research has been published in the Journal of Experimental Medicine. As cancer cells mutate, they create new proteins on their surface that could be targets for vaccines;

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November 24, 2014 by Suzanne Elvidge in Big data, Big data in research, Data analytics, Healthcare big data analysis

New drugs for old: Big data pinpoints a way to prevent stent disease

Patients who have had their arteries unblocked using stents or balloon angioplasty can find that their arteries become obstructed again, sometimes after only a few months. Researchers at Stanford University School of Medicine have used big data to repurpose a marketed cancer drug. This has potential to create a better

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November 18, 2014 by Suzanne Elvidge in Big data in research, Data analytics, Healthcare big data analysis

Casting a data analytics eye over glaucoma

Understanding more about the genetics underlying glaucoma, where increased pressure within the eye can lead to irreversible blindness, could lead to personalised medicine for different forms of the disease. Researchers at the University of Liverpool, in the UK, have used data analytics and genome sequencing to find out more about

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